GINS2 antibody (AA 1-185)

Catalog No. ABIN7599047

The Rabbit Polyclonal anti-GINS2 antibody has been validated for ELISA, WB and FACS. It is suitable to detect GINS2 in samples from Human.

Quick Overview for GINS2 antibody (AA 1-185) (ABIN7599047)

Target: GINS2 (GINS Complex Subunit 2 (Psf2 Homolog) (GINS2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GINS2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Flow Cytometry (FACS)

Product Details anti-GINS2 Antibody

Binding Specificity: AA 1-185

Purpose: Anti-PSF2/GINS2 Antibody Picoband®

Characteristics: Anti-PSF2/GINS2 Antibody Picoband® (ABIN7599047). Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PSF2/GINS2 recombinant protein (Position: M1-F185). Human GINS2 shares 92.4% amino acid (aa) sequence identity with mouse GINS2.

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Takayama, Y., Kamimura, Y., Okawa, M., Muramatsu, S., Sugino, A., Araki, H. GINS, a novel multiprotein complex required for chromosomal DNA replication in budding yeast. Genes Dev. 17: 1153-1165, 2003. 2. Ueno, M., Itoh, M., Kong, L., Sugihara, K., Asano, M., Takakura, N. PSF1 is essential for early embryogenesis in mice. Molec. Cell Biol. 25: 10528-10532, 2005.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for GINS2

Target: GINS2 (GINS Complex Subunit 2 (Psf2 Homolog) (GINS2))

Alternative Name: GINS2

Background: DNA replication complex GINS protein PSF2 is a protein that in humans is encoded by the GINS2 gene. The yeast heterotetrameric GINS complex is made up of Sld5 (GINS4, MIM 610611), Psf1 (GINS1, MIM 610608), Psf2, and Psf3 (GINS3, MIM 610610). The formation of this complex is essential for the initiation of DNA replication in yeast and Xenopus egg extracts (Ueno et al., 2005 [PubMed 16287864]). See GINS1 for additional information about the GINS complex.

Molecular Weight: 21 kDa

Gene ID: 51659

UniProt: Q9Y248

Pathways: DNA Replication, Synthesis of DNA