STARD10 antibody (AA 1-273)

Catalog No. ABIN7599199

This Rabbit Polyclonal antibody specifically detects STARD10 in ELISA, WB, ICC, IF and FACS. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for STARD10 antibody (AA 1-273) (ABIN7599199)

Target: STARD10 (StAR-Related Lipid Transfer (START) Domain Containing 10 (STARD10))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STARD10 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FACS)

Product Details anti-STARD10 Antibody

Binding Specificity: AA 1-273

Purpose: Anti-PCTP-L/STARD10 Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-PCTP-L/STARD10 Antibody (ABIN7599199). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PCTP-L/STARD10 recombinant protein (Position: M1-E273).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry(Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for STARD10

Target: STARD10 (StAR-Related Lipid Transfer (START) Domain Containing 10 (STARD10))

Alternative Name: STARD10

Background:

Synonyms: Neutrophil defensin 1,Defensin, alpha 1,HNP-1,HP-1,HP1,HP 1-56,Neutrophil defensin 2,HNP-2,HP-2,HP2,DEFA1,DEF1, DEFA2, MRS,DEFA1B,

Tissue Specificity: Expressed in immature but not mature T-cells. Also found in CD34+ cells from peripheral blood, CD34+ precursors from umbilical cord blood and adult bone marrow.

Background: StAR-related lipid transfer protein 10 (STARD10) or PCTP-like protein is a lipid transfer protein that in humans is encoded by the STARD10 gene. StarD10 is a dual-specificity lipid transfer protein capable of shuttling phosphatidylcholine (PC) and phosphatidylethanolamine (PE) between membranes in vitro, changes in membrane composition of PC and PE occur before the morphological tumorigenic events. Interestingly, STARD10 has been described to be highly expressed in 35-40 % of ERBB2-positive breast cancers. StarD10 was initially discovered based on its cross-reactivity with a phosphoserine-specific antibody in mammary tumors from Neu/ErbB2 transgenic mice and subsequently isolated from SKBR3 human breast carcinoma cells using a multistep biochemical purification strategy. StarD10 contains a steroidogenic acute regulatory protein (StAR/StarD1)-related lipid transfer (START) domain that is thought to mediate binding of lipids. STARD10 is highly expressed in the liver and has been shown to transfer phosphatidylcholine.

Molecular Weight: 37 kDa

Gene ID: 10809

UniProt: Q9Y365