CDC123 antibody (AA 1-336)

Catalog No. ABIN7599284

The Rabbit Polyclonal anti-CDC123 antibody has been validated for WB, ELISA, IHC, FACS, IF and ICC. It is suitable to detect CDC123 in samples from Human.

Quick Overview for CDC123 antibody (AA 1-336) (ABIN7599284)

Target: CDC123 (Cell Division Cycle 123 Homolog (CDC123))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDC123 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-CDC123 Antibody

Binding Specificity: AA 1-336

Purpose: Anti-CDC123 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-C Antibody Picoband® (ABIN7599284). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human CDC123 recombinant protein (Position: M1-D336).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Hartz, P. A. Personal Communication. Baltimore, Md. 9/29/2017. 2. Okuda, A., Kimura, G. An amino acid change in novel protein D123 is responsible for temperature-sensitive G1-phase arrest in a mutant of rat fibroblast line 3Y1. Exp. Cell Res. 223: 242-249, 1996. 3. Onisto, M., Zeilante, P., Scannapieco, P., Pellati, D., Pozza, M., Caenazzo, C., Negro, A., Garbisa, S. Expression study on D123 gene product: evidence for high positivity in testis. Exp. Cell Res. 242: 451-459, 1998.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for CDC123

Target: CDC123 (Cell Division Cycle 123 Homolog (CDC123))

Alternative Name: CDC123

Background:

Synonyms: Neuropeptides B/W receptor type 1, G-protein coupled receptor 7, NPBWR1, GPR7

Tissue Specificity: Found in cerebellum and frontal cortex. Detected at high levels in hippocampus, amygdala and trachea, at moderate levels in fetal brain, pituitary gland and prostate. Not in caudate, accumbens, kidney or liver. Also detected at high levels in lung carcinoma.

Background: Cell division cycle protein 123 homolog is a protein that in humans is encoded by the CDC123 gene. It is mapped to chromosome 10p14-p13. CDC123 is predicted to function as an assembly factor for eukaryotic translation initiation factor-2, which recruits initiator met-tRNA to the 40S ribosome to begin protein synthesis.

Molecular Weight: 45 kDa

Gene ID: 8872

UniProt: O75794