ODC1 antibody (AA 1-450)

Catalog No. ABIN7599405

This anti-ODC1 antibody is a Rabbit Polyclonal antibody detecting ODC1 in WB and ELISA. Suitable for Human, Rat and Mouse.

Quick Overview for ODC1 antibody (AA 1-450) (ABIN7599405)

Target: ODC1 (Ornithine Decarboxylase 1 (ODC1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ODC1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ODC1 Antibody

Binding Specificity: AA 1-450

Purpose: Anti-ODC1 Antibody Picoband®

Characteristics: Anti-ODC1 Antibody Picoband® (ABIN7599405). Tested in WB, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human ODC1 recombinant protein (Position: M1-H450). Human ODC1 shares 90.9% and 91.6% amino acid (aa) sequence identity with mouse and rat ODC1, respectively.

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Alhonen-Hongisto, L., Leinonen, P., Sinervirta, R., Laine, R., Winqvist, R., Alitalo, K., Janne, O. A., Janne, J. Mouse and human ornithine decarboxylase genes: methylation polymorphism and amplification. Biochem. J. 242: 205-210, 1987. 2. Brabant, M., McConlogue, L., van Daalen Wetters, T., Coffino, P. Mouse ornithine decarboxylase gene: cloning, structure, and expression. Proc. Nat. Acad. Sci. 85: 2200-2204, 1988. 3. Bupp, C. P., Schultz, C. R., Uhl, K. L., Rajasekaran, S., Bachmann, A. S. Novel de novo pathogenic variant in the ODC1 gene in a girl with developmental delay, alopecia, and dysmorphic features. Am. J. Med. Genet. 176A: 2548-2553, 2018.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for ODC1

Target: ODC1 (Ornithine Decarboxylase 1 (ODC1))

Alternative Name: ODC1

Background: This gene encodes the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyzes ornithine to putrescine. The activity level for the enzyme varies in response to growth-promoting stimuli and exhibits a high turnover rate in comparison to other mammalian proteins. Originally localized to both chromosomes 2 and 7, the gene encoding this enzyme has been determined to be located on 2p25, with a pseudogene located on 7q31-qter. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified.

Molecular Weight: 51 kDa

Gene ID: 4953

UniProt: P11926