AHRR antibody (AA 108-180)

Catalog No. ABIN7599680

Product Details anti-AHRR Antibody

Target: AHRR (Aryl-Hydrocarbon Receptor Repressor (AHRR))

Binding Specificity: AA 108-180

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AHRR antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purpose: Anti-AHRR Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-AHRR Antibody Picoband® (ABIN7599680). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human AHRR recombinant protein (Position: L108-D180).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse
ELISA, 0.1-0.5 μg/mL, -
1. Baba, T., Mimura, J., Gradin, K., Kuroiwa, A., Watanabe, T., Matsuda, Y., Inazawa, J., Sogawa, K., Fujii-Kuriyama, Y. Structure and expression of the Ah receptor repressor gene. J. Biol. Chem. 276: 33101-33110, 2001. 2. Mimura, J., Ema, M., Sogawa, K., Fujii-Kuriyama, Y. Identification of a novel mechanism of regulation of Ah (dioxin) receptor function. Genes Dev. 13: 20-25, 1999. 3. Nagase, T., Ishikawa, K., Kikuno, R., Hirosawa, M., Nomura, N., Ohara, O. Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. DNA Res. 6: 337-345, 1999.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for AHRR

Target: AHRR (Aryl-Hydrocarbon Receptor Repressor (AHRR))

Alternative Name: AHRR (AHRR Products)

Background:

Synonyms: Platelet endothelial cell adhesion molecule, PECAM-1, CD31, Pecam1, Pecam

Tissue Specificity: Isoform 1 and isoform 3 are expressed in lung and platelets.

Background: The aryl-hydrocarbon receptor repressor also known as AHRR is a human gene. The protein encoded by this gene participates in the aryl hydrocarbon receptor (AhR) signaling cascade, which mediates dioxin toxicity, and is involved in regulation of cell growth and differentiation. It functions as a feedback modulator by repressing AhR-dependent gene expression. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Molecular Weight: 76 kDa

Gene ID: 57491

Pathways: Steroid Hormone Biosynthesis, Regulation of Lipid Metabolism by PPARalpha