RNGTT antibody (AA 11-438)

Catalog No. ABIN7599723

This anti-RNGTT antibody is a Rabbit Polyclonal antibody detecting RNGTT in WB, IHC, IF, ELISA, ICC and FACS. Suitable for Human.

Quick Overview for RNGTT antibody (AA 11-438) (ABIN7599723)

Target: RNGTT (RNA Guanylyltransferase and 5'-Phosphatase (RNGTT))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RNGTT antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)

Product Details anti-RNGTT Antibody

Binding Specificity: AA 11-438

Purpose: Anti-RNGTT Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-RNGTT Antibody Picoband® (ABIN7599723). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human RNGTT recombinant protein (Position: L11-D438).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Pillutla, R. C., Shimamoto, A., Furuichi, Y., Shatkin, A. J. Human mRNA capping enzyme (RNGTT) and cap methyltransferase (RNMT) map to 6q16 and 18p11.22-p11.23, respectively. Genomics 54: 351-353, 1998. 2. Tsukamoto, T., Shibagaki, Y., Murakoshi, T., Suzuki, M., Nakamura, A., Gotoh, H., Mizumoto, K. Cloning and characterization of two human cDNAs encoding the mRNA capping enzyme. Biochem. Biophys. Res. Commun. 243: 101-108, 1998. 3. Yamada-Okabe, T., Doi, R., Shimmi, O., Arisawa, M., Yamada-Okabe, H. Isolation and characterization of a human cDNA for mRNA 5-prime-capping enzyme. Nucleic Acids Res. 26: 1700-1706, 1998.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for RNGTT

Target: RNGTT (RNA Guanylyltransferase and 5'-Phosphatase (RNGTT))

Alternative Name: RNGTT

Background:

Synonyms: B-cell differentiation antigen CD72, Lyb-2, CD72, CD72

Tissue Specificity: Pre-B-cells and B-cells but not terminally differentiated plasma cells.

Background: mRNA-capping enzyme is a protein that in humans is encoded by the RNGTT gene. Enables mRNA guanylyltransferase activity and triphosphatase activity. Involved in 7-methylguanosine mRNA capping. Predicted to be located in nucleoplasm.

Molecular Weight: 69 kDa

Gene ID: 8732

UniProt: O60942