TOMM40 antibody (AA 111-315)

Catalog No. ABIN7599738

This anti-TOMM40 antibody is a Rabbit Polyclonal antibody detecting TOMM40 in WB, ELISA, IHC, IF, FACS and ICC. Suitable for Human.

Quick Overview for TOMM40 antibody (AA 111-315) (ABIN7599738)

Target: TOMM40 (Translocase of Outer Mitochondrial Membrane 40 Homolog (TOMM40))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TOMM40 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Product Details anti-TOMM40 Antibody

Binding Specificity: AA 111-315

Purpose: Anti-TOMM40 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-TOMM40 Antibody Picoband® (ABIN7599738). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human TOMM40 recombinant protein (Position: N111-K315).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Freitas, E. M., Zhang, W. J., Lalonde, J.-P., Tay, G. K., Gaudieri, S., Ashworth, L. K., van Bockxmeer, F. M., Dawkins, R. L. Sequencing of 42kb of the APO E-C2 gene cluster reveals a new gene: PEREC1. DNA Seq. 9: 89-101, 1998. 2. Gabriel, K., Egan, B., Lithgow, T. Tom40, the import channel of the mitochondrial outer membrane, plays an active role in sorting imported proteins. EMBO J. 22: 2380-2386, 2003. 3. Humphries, A. D., Streimann, I. C., Stojanovski, D., Johnston, A. J., Yano, M., Hoogenraad, N. J., Ryan, M. T. Dissection of the mitochondrial import and assembly pathway for human Tom40. J. Biol. Chem. 280: 11535-11543, 2005.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for TOMM40

Target: TOMM40 (Translocase of Outer Mitochondrial Membrane 40 Homolog (TOMM40))

Alternative Name: TOMM40

Background:

Synonyms: IFNGR2 protein, Interferon gamma receptor 2, IFNGR2, mCG_11456

Tissue Specificity: Wide tissue distribution (highest in the pancreas and very low in brain). Closely associated with the basal layer of cells in epithelia and the endothelium of blood vessel walls.

Background: Translocase of outer mitochondrial membrane 40 homolog (yeast), also known as TOMM40, is a protein which in humans is encoded by the TOMM40 gene. The protein encoded by this gene is localized in the outer membrane of the mitochondria. It is the channel-forming subunit of the translocase of the mitochondrial outer membrane (TOM) complex that is essential for import of protein precursors into mitochondria. Alternatively spliced transcript variants have been found for this gene.

Molecular Weight: 38 kDa

Gene ID: 10452

UniProt: O96008