CEP55 antibody (AA 115-464)

Catalog No. ABIN7599765

This anti-CEP55 antibody is a Rabbit Polyclonal antibody detecting CEP55 in WB, ELISA and FACS. Suitable for Human.

Quick Overview for CEP55 antibody (AA 115-464) (ABIN7599765)

Target: CEP55 (Centrosomal Protein 55kDa (CEP55))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CEP55 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-CEP55 Antibody

Binding Specificity: AA 115-464

Purpose: Anti-CEP55 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-CEP55 Antibody Picoband® (ABIN7599765). Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human CEP55 recombinant protein (Position: E115-K464). Human CEP55 shares 76.3% and 78% amino acid (aa) sequence identity with mouse and rat CEP55, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL
1. Bondeson, M.-L., Ericson, K., Gudmundsson, S., Ameur, A., Ponten, F., Wesstrom, J., Frykholm, C., Wilbe, M. A nonsense mutation in CEP55 defines a new locus for a Meckel-like syndrome, an autosomal recessive lethal fetal ciliopathy. Clin. Genet. 92: 510-516, 2017. 2. Chen, C.-H., Chien, C.-Y., Huang, C.-C., Hwang, C.-F., Chuang, H.-C., Fang, F.-M., Huang, H.-Y., Chen, C.-M., Liu, H.-L., Huang, C.-Y. F. Expression of FLJ10540 is correlated with aggressiveness of oral cavity squamous cell carcinoma by stimulating cell migration and invasion through increased FOXM1 and MMP-2 activity. Oncogene 28: 2723-2737, 2009. 3. Chen, C.-H., Lu, P.-J., Chen, Y.-C., Fu, S.-L., Wu, K.-J., Tsou, A.-P., Lee, Y.-C. G., Lin, T.-C. E., Hsu, S.-L., Lin, W.-J., Huang, C.-Y. F., Chou, C.-K. FLJ10540-elicited cell transformation is through the activation of PI3-kinase/AKT pathway. Oncogene 26: 4272-4283, 2007.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for CEP55

Target: CEP55 (Centrosomal Protein 55kDa (CEP55))

Alternative Name: CEP55

Background:

Synonyms: CEP55, C10orf3, URCC6, Centrosomal protein of 55 kDa, Cep55, Up-regulated in colon cancer 6

Background: Centrosomal protein of 55 kDa (Cep55), is a protein that in humans is encoded by the CEP55 gene. Enables identical protein binding activity. Involved in cranial skeletal system development, establishment of protein localization, and midbody abscission. Acts upstream of or within mitotic cytokinesis. Located in Flemming body and centrosome. Implicated in multinucleated neurons, anhydramnios, renal dysplasia, cerebellar hypoplasia and hydranencephaly.

Molecular Weight: 54 kDa

Gene ID: 55165