GLMN antibody (AA 153-574)

Catalog No. ABIN7600137

The Rabbit Polyclonal anti-GLMN antibody has been validated for WB, ELISA and FACS. It is suitable to detect GLMN in samples from Human, Mouse and Rat.

Quick Overview for GLMN antibody (AA 153-574) (ABIN7600137)

Target: GLMN (Glomulin, FKBP Associated Protein (GLMN))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GLMN antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-GLMN Antibody

Binding Specificity: AA 153-574

Purpose: Anti-GLMN Antibody Picoband®

Characteristics: Anti-GLMN Antibody Picoband® (ABIN7600137). Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human GLMN recombinant protein (Position: Q153-R574). Human GLMN shares 85.4% amino acid (aa) sequence identity with mouse GLMN.

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Arai, T., Kasper, J. S., Skaar, J. R., Ali, S. H., Takahashi, C., DeCaprio, J. A. Targeted disruption of p185/Cul7 gene results in abnormal vascular morphogenesis. Proc. Nat. Acad. Sci. 100: 9855-9860, 2003. 2. Brouillard, P., Boon, L. M., Mulliken, J. B., Enjolras, O., Ghassibe, M., Warman, M. L., Tan, O. T., Olsen, B. R., Vikkula, M. Mutations in a novel factor, glomulin, are responsible for glomuvenous malformations ('glomangiomas'). Am. J. Hum. Genet. 70: 866-874, 2002. 3. Brouillard, P., Olsen, B. R., Vikkula, M. High-resolution physical and transcript map of the locus for venous malformations with glomus cells (VMGLOM) on chromosome 1p21-p22. Genomics 67: 96-101, 2000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for GLMN

Target: GLMN (Glomulin, FKBP Associated Protein (GLMN))

Alternative Name: GLMN

Background: Glomulin is a protein that in humans is encoded by the GLMN gene. This gene encodes a phosphorylated protein that is a member of a Skp1-Cullin-F-box-like complex. The protein is essential for normal development of the vasculature and mutations in this gene have been associated with glomuvenous malformations, also called glomangiomas. Multiple splice variants encoding different isoforms have been found for this gene.

Molecular Weight: 68 kDa

Gene ID: 11146

UniProt: Q92990

Pathways: Tube Formation