MOAP1 antibody (AA 18-341)

Catalog No. ABIN7600332

This Rabbit Polyclonal antibody specifically detects MOAP1 in WB, ELISA, IHC and FACS. It exhibits reactivity toward Human.

Quick Overview for MOAP1 antibody (AA 18-341) (ABIN7600332)

Target: MOAP1 (Modulator of Apoptosis 1 (MOAP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MOAP1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Product Details anti-MOAP1 Antibody

Binding Specificity: AA 18-341

Purpose: Anti-MOAP1 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-MOAP1 Antibody Picoband® (ABIN7600332). Tested in ELISA, IHC, WB, Flow Cytometry applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human MOAP1 recombinant protein (Position: R18-L341).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry, 2-5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Baksh, S., Tommasi, S., Fenton, S., Yu, V. C., Martins, L. M., Pfeifer, G. P., Latif, F., Downward, J., Neel, B. G. The tumor suppressor RASSF1A and MAP-1 link death receptor signaling to Bax conformational change and cell death. Molec. Cell 18: 637-650, 2005. 2. Gross, M. B. Personal Communication. Baltimore, Md. 2/27/2014. 3. Tan, K. O., Tan, K. M. L., Chan, S.-L., Yee, K. S. Y., Bevort, M., Ang, K. C., Yu, V. C. MAP-1, a novel proapoptotic protein containing a BH3-like motif that associates with Bax through its Bcl-2 homology domains. J. Biol. Chem. 276: 2802-2807, 2001.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for MOAP1

Target: MOAP1 (Modulator of Apoptosis 1 (MOAP1))

Alternative Name: MOAP1

Background:

Synonyms: BMP and activin membrane-bound inhibitor homolog, Non-metastatic gene A protein, Putative transmembrane protein, NMA, BAMBI, NMA

Tissue Specificity: Expressed in adult liver.

Background: Modulator of apoptosis 1 is a protein that in humans is encoded by the MOAP1 gene. The protein encoded by this gene was identified by its interaction with apoptosis regulator BAX protein. This protein contains a Bcl-2 homology 3 (BH3)-like motif, which is required for the association with BAX. When overexpressed, this gene has been shown to mediate caspase-dependent apoptosis.

Molecular Weight: 35 kDa

Gene ID: 64112

Pathways: Positive Regulation of Endopeptidase Activity