STAMBP antibody (AA 187-424)

Catalog No. ABIN7600388

This anti-STAMBP antibody is a Rabbit Polyclonal antibody detecting STAMBP in WB, ELISA, IHC, IF, ICC and FACS. Suitable for Human, Mouse, Rat and Monkey.

Quick Overview for STAMBP antibody (AA 187-424) (ABIN7600388)

Target: STAMBP (STAM Binding Protein (STAMBP))

Reactivity: Human, Mouse, Rat, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STAMBP antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Product Details anti-STAMBP Antibody

Binding Specificity: AA 187-424

Purpose: Anti-STAMBP Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-STAMBP Antibody Picoband® (ABIN7600388). Tested in WB, IHC, ICC/IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Monkey, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human STAMBP recombinant protein (Position: K187-R424). Human STAMBP shares 79% and 79.8% amino acid (aa) sequence identity with mouse and rat STAMBP, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Monkey, Mouse
Immunohistochemistry, 2-5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL
1. Carter, M. T., Geraghty, M. T., De La Cruz, L., Reichard, R. R., Boccuto, L., Schwartz, C. E., Clericuzio, C. L. A new syndrome with multiple capillary malformations, intractable seizures, and brain and limb anomalies. Am. J. Med. Genet. 155A: 301-306, 2011. 2. Ishii, N., Owada, Y., Yamada, M., Miura, S., Murata, K., Asao, H., Kondo, H., Sugamura, K. Loss of neurons in the hippocampus and cerebral cortex of AMSH-deficient mice. Molec. Cell. Biol. 21: 8626-8637, 2001. 3. Isidor, B., Barbarot, S., Beneteau, C., Le Caignec, C., David, A. Multiple capillary skin malformations, epilepsy, microcephaly, mental retardation, hypoplasia of the distal phalanges: report of a new case and further delineation of a new syndrome. (Letter) Am. J. Med. Genet. 155A: 1458-1460, 2011.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for STAMBP

Target: STAMBP (STAM Binding Protein (STAMBP))

Alternative Name: STAMBP

Background:

Synonyms: STAMBP, AMSH, STAM-binding protein, EC 3.4.19.-, Associated molecule with the SH3 domain of STAM, Endosome-associated ubiquitin isopeptidase

Background: Cytokine-mediated signal transduction in the JAK-STAT cascade requires the involvement of adaptor molecules. One such signal-transducing adaptor molecule contains an SH3 domain that is required for induction of MYC and cell growth. The protein encoded by this gene binds to the SH3 domain of the signal-transducing adaptor molecule, and plays a critical role in cytokine-mediated signaling for MYC induction and cell cycle progression. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene.

Molecular Weight: 48 kDa

Gene ID: 10617

UniProt: O95630