alpha Fetoprotein antibody (AA 19-258)
Quick Overview for alpha Fetoprotein antibody (AA 19-258) (ABIN7600406)
Target
See all alpha Fetoprotein (AFP) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 19-258
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Purpose
- Anti-alpha 1 Fetoprotein/AFP Antibody
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Cross-Reactivity (Details)
- No cross-reactivity with other proteins.
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Characteristics
- Anti-alpha 1 Fetoprotein/AFP Antibody (ABIN7600406). Tested in ELISA, WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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Purification
- Immunogen affinity purified.
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Immunogen
- E.coli-derived human alpha 1 Fetoprotein/AFP recombinant protein (Position: R19-L258).
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Isotype
- IgG
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Application Notes
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Western blot, 0.25-0.5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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Storage
- 4 °C,-20 °C
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Storage Comment
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- alpha Fetoprotein (AFP) (alpha-Fetoprotein (AFP))
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Alternative Name
- AFP
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Background
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Synonyms: Alpha-fetoprotein, Alpha-1-fetoprotein, Alpha-fetoglobulin, Afp
Tissue Specificity: Plasma.
Background: AFP, also called Alpha-fetoprotein, alpha-fetoprotein, is a protein that in humans is encoded by the AFP gene. It is mapped to 4q13.3. The level of AFP in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. In rodents AFP binds estradiol to prevent the transport of this hormone across the placenta to the fetus. The main function of this is to prevent the virilization of female fetuses. Moreover, it has an important role as a diagnostic marker, especially in certain tumors and liver diseases of childhood. AFP is also used to test the potential usefulness of plasma alpha fetoprotein determination as a diagnostic marker in biliary atresia, hepatitis, and yolk sac derived tumours.
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Molecular Weight
- 69 kDa
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Gene ID
- 174
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UniProt
- P02771
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Pathways
- C21-Steroid Hormone Metabolic Process
Target
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