VRK2 antibody (AA 19-491)

Catalog No. ABIN7600420

The Rabbit Polyclonal anti-VRK2 antibody has been validated for WB, ELISA and FACS. It is suitable to detect VRK2 in samples from Human.

Quick Overview for VRK2 antibody (AA 19-491) (ABIN7600420)

Target: VRK2 (Vaccinia Related Kinase 2 (VRK2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VRK2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-VRK2 Antibody

Binding Specificity: AA 19-491

Purpose: Anti-VRK2 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-VRK2 Antibody Picoband® (ABIN7600420). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human VRK2 recombinant protein (Position: K19-R491).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Nezu, J., Oku, A., Jones, M. H., Shimane, M. Identification of two novel human putative serine/threonine kinases, VRK1 and VRK2, with structural similarity to vaccinia virus B1R kinase. Genomics 45: 327-331, 1997.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for VRK2

Target: VRK2 (Vaccinia Related Kinase 2 (VRK2))

Alternative Name: VRK2

Background:

Synonyms: NACHT, LRR and PYD domains-containing protein 2, Nucleotide-binding site protein 1, PYRIN domain and NACHT domain-containing protein 1, PYRIN-containing APAF1-like protein 2, NLRP2, NALP2, NBS1, PAN1, PYPAF2

Tissue Specificity: Expressed at high levels in lung, placenta and thymus and at lower levels in ovary, intestine and brain.

Background: Serine/threonine-protein kinase VRK2 is an enzyme that in humans is encoded by the VRK2 gene. This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. The encoded protein acts as an effector of signaling pathways that regulate apoptosis and tumor cell growth. Variants in this gene have been associated with schizophrenia. Alternative splicing results in multiple transcript variants that differ in their subcellular localization and biological activity.

Molecular Weight: 50 kDa

Gene ID: 7444

UniProt: Q86Y07