Pannexin 2 antibody (AA 19-677)

Catalog No. ABIN7600425

This Rabbit Polyclonal antibody specifically detects Pannexin 2 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for Pannexin 2 antibody (AA 19-677) (ABIN7600425)

Target: Pannexin 2 (PANX2)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Pannexin 2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Pannexin 2 Antibody

Binding Specificity: AA 19-677

Purpose: Anti-Pannexin 2/PANX2 Picoband® Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-Pannexin 2/PANX2 Picoband® Antibody (ABIN7600425). Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Pannexin 2/PANX2 recombinant protein (Position: E19-F677).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Bruzzone, R., Hormuzdi, S. G., Barbe, M. T., Herb, A., Monyer, H. Pannexins, a family of gap junction proteins expressed in brain. Proc. Nat. Acad. Sci. 100: 13644-13649, 2003. 2. Hartz, P. A. Personal Communication. Baltimore, Md. 1/23/2004.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for Pannexin 2

Target: Pannexin 2 (PANX2)

Alternative Name: PANX2

Background:

Synonyms: Pannexin-2, PANX2

Tissue Specificity: Expressed in fetal and adult brain. Also detected in fetal liver and skeletal muscle, but not in their adult counterparts.

Background: Pannexin 2 is a protein that in humans is encoded by the PANX2 gene. It is mapped to 22q13.33. The protein encoded by this gene belongs to the innexin family. Innexin family members are the structural components of gap junctions. This protein and pannexin 1 are abundantly expressed in central nervous system (CNS) and are coexpressed in various neuronal populations. Studies in Xenopus oocytes suggest that this protein alone and in combination with pannexin 1 may form cell type-specific gap junctions with distinct properties. Multiple transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 74 kDa

Gene ID: 56666