LRRC32 antibody (AA 20-544)

Catalog No. ABIN7600555

The Rabbit Polyclonal anti-LRRC32 antibody has been validated for WB and ELISA. It is suitable to detect LRRC32 in samples from Human.

Quick Overview for LRRC32 antibody (AA 20-544) (ABIN7600555)

Target: LRRC32 (Leucine Rich Repeat Containing 32 (LRRC32))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LRRC32 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-LRRC32 Antibody

Binding Specificity: AA 20-544

Purpose: Anti-LRRC32 Picoband® Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-LRRC32 Picoband® Antibody (ABIN7600555). Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human LRRC32 recombinant protein (Position: H20-R544).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Lienart, S., Merceron, R., Vanderaa, C., Lambert, F., Colau, D., Stockis, J., van der Woning, B., De Haard, H., Saunders, M., Coulie, P. G., Savvides, S. N., Lucas, S. Structural basis of latent TGF-beta-1 presentation and activation by GARP on human regulatory T cells. Science 362: 952-956, 2018. 2. Ollendorff, V., Noguchi, T., deLapeyriere, O., Birnbaum, D. The GARP gene encodes a new member of the family of leucine-rich repeat-containing proteins. Cell Growth Diff. 5: 213-219, 1994. 3. Ollendorff, V., Szepetowski, P., Mattei, M.-G., Gaudray, P., Birnbaum, D. New gene in the homologous human 11q13-q14 and mouse 7F chromosomal regions. Mammalian Genome 2: 195-200, 1992.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for LRRC32

Target: LRRC32 (Leucine Rich Repeat Containing 32 (LRRC32))

Alternative Name: LRRC32

Background:

Synonyms: Transforming growth factor beta activator LRRC32, Garpin, Glycoprotein A repetitions predominant, GARP, Leucine-rich repeat-containing protein 32, LRRC32, D11S833E

Tissue Specificity: Heart, placenta, skeletal muscle, kidney, lung and pancreas.

Background: Leucine-rich repeat protein 32 (LRRC32), also known as GARP (glycoprotein A repetitions predominant), is an 80 kDa type I transmembrane glycoprotein. It is mapped to 11q13.5. This gene encodes a type I membrane protein which contains 20 leucine-rich repeats. Alterations in the chromosomal region 11q13-11q14 are involved in several pathologies.

Molecular Weight: 72 kDa

Gene ID: 2615

UniProt: Q14392

Pathways: Activated T Cell Proliferation