METTL11A antibody (AA 21-223)
Quick Overview for METTL11A antibody (AA 21-223) (ABIN7600601)
Target
See all METTL11A AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 21-223
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Purpose
- Anti-METTL11A/NTMT1 Antibody Picoband®
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Cross-Reactivity (Details)
- No cross-reactivity with other proteins
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Characteristics
- Anti-METTL11A/NTMT1 Antibody Picoband® (ABIN7600601). Tested in ELISA, IF, IHC, ICC, WB, Flow Cytometry applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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Purification
- Immunogen affinity purified.
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Immunogen
- E.coli-derived human METTL11A/NTMT1 recombinant protein (Position: K21-R223).
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Isotype
- IgG
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Application Notes
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Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry, 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Gross, M. B. Personal Communication. Baltimore, Md. 7/17/2014. 2. Schaner Tooley, C. E., Petkowski, J. J., Muratore-Schroeder, T. L., Balsbaugh, J. L., Shabanowitz, J., Sabat, M., Minor, W., Hunt, D. F., Macara, I. G. NRMT is an alpha-N-methyltransferase that methylates RCC1 and retinoblastoma protein. Nature 466: 1125-1128, 2010. -
Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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Storage
- 4 °C,-20 °C
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Storage Comment
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- METTL11A (Methyltransferase Like 11A (METTL11A))
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Alternative Name
- NTMT1
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Background
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Synonyms: Protein NDRG3,N-myc downstream-regulated gene 3 protein,NDRG3,
Tissue Specificity: Ubiquitous. Highly expressed in brain. .
Background: The METTL11A gene encodes an N-terminal methyltransferase for the RAN (MIM 601179) guanine nucleotide exchange factor regulator of chromosome condensation 1 (RCC1, MIM 179710). METTL11A enzyme alpha-N-methylates other protein targets such as SET (MIM 600960) and RB (MIM 180200).
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Molecular Weight
- 25 kDa
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Gene ID
- 28989
Target
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