LRRC40 antibody (AA 21-598)

Catalog No. ABIN7600626

Product Details anti-LRRC40 Antibody

Target: LRRC40 (Leucine Rich Repeat Containing 40 (LRRC40))

Binding Specificity: AA 21-598

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LRRC40 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purpose: Anti-LRRC40 Antibody Picoband®

Characteristics: Anti-LRRC40 Antibody Picoband® (ABIN7600626). Tested in WB, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human LRRC40 recombinant protein (Position: R21-D598). Human LRRC40 shares 84.1% amino acid (aa) sequence identity with mouse LRRC40.

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Pijuan, J. , Juan Darío Ortigoza-Escobar, Ortiz, J. , Adrián Alcalá, María José Calvo, & Cubells, M. , et al. (2021). Plxna2 and lrrc40 as candidate genes in autism spectrum disorder. Autism Research. 2. Liu, H. , Cui, J. , Zhang, Y. , Niu, M. , Xue, X. , & Yin, H. , et al. (2019). Mass spectrometry-based proteomic analysis of fscn1-interacting proteins in laryngeal squamous cell carcinoma cells. IUBMB Life, 71(11). 3. Wang, Y. , Du, S. , Zhu, C. , Wang, C. , & Cai, Q. . (2020). Stub1 is targeted by the sumo-interacting motif of ebna1 to maintain epstein-barr virus latency. PLoS Pathogens, 16(3), e1008447.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for LRRC40

Target: LRRC40 (Leucine Rich Repeat Containing 40 (LRRC40))

Alternative Name: LRRC40 (LRRC40 Products)

Background: Leucine rich repeat containing 40 (LRRC40) is a protein that in humans is encoded by the LRRC40 gene. The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic α/β horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. The primary function of these motifs is to provide a versatile structural framework to mediate the formation of protein-protein interactions. LRRs are present in a variety of proteins with diverse structure and function, including innate immunity and nervous system development. Several human diseases are associated with mutations in genes encoding LRR-containing proteins. LRRC40 (leucine rich repeat containing 40) is a 602 amino acid protein that contains 20 LRR (leucine-rich) repeats.

Molecular Weight: 72 kDa

Gene ID: 55631

UniProt: Q9H9A6