Integrator Complex Subunit 14 (INTS14) (AA 27-271) antibody

Catalog No. ABIN7601005

The Rabbit Polyclonal anti- antibody has been validated for ELISA and WB. It is suitable to detect in samples from Human.

Quick Overview for Integrator Complex Subunit 14 (INTS14) (AA 27-271) antibody (ABIN7601005)

Target: Integrator Complex Subunit 14 (INTS14)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details

Binding Specificity: AA 27-271

Purpose: Anti-INTS14 Antibody Picoband®

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Anti-INTS14 Antibody Picoband® (ABIN7601005). Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human INTS14 recombinant protein (Position: R27-H271). Human INTS14 shares 99.2% and 98.4% amino acid (aa) sequence identity with mouse and rat INTS14, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Pfleiderer, M. M. , & Galej, W. P. . (2021). Structure of the catalytic core of the integrator complex. Molecular Cell, 81(Suppl 1). 2. Beckedorff, F. , Blumenthal, E. , Dasilva, L. F. , Aoi, Y. , Cingaram, P. R. , & Yue, J. , et al. (2020). The human integrator complex facilitates transcriptional elongation by endonucleolytic cleavage of nascent transcripts. Cell Reports, 32(3). 3. Sabath, K. , Stubli, M. L. , Marti, S. , Leitner, A. , & Jonas, S. . (2020). Ints10-ints13-ints14 form a functional module of integrator that binds nucleic acids and the cleavage module. Nature Communications, 11(1).

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details

Target: Integrator Complex Subunit 14 (INTS14)

Alternative Name: INTS14

Background:

Synonyms: 70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70(S6K) alpha antibody, p70(S6K)-alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70 kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody

Tissue Specificity: Expressed in all tissues.

Background: INTS14 is an uncharacterized protein that bears a P-loop nucleoside triphosphate hydrolase (NTPase) domain.

Molecular Weight: 68 kDa

Gene ID: 81556