LINGO2 antibody (AA 28-513)

Catalog No. ABIN7601082

Product Details anti-LINGO2 Antibody

Target: LINGO2 (Leucine Rich Repeat and Ig Domain Containing 2 (LINGO2))

Binding Specificity: AA 28-513

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LINGO2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purpose: Anti-LINGO2 Antibody Picoband®

Characteristics: Anti-LINGO2 Antibody Picoband® (ABIN7601082). Tested in WB, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human LINGO2 recombinant protein (Position: C28-R513). Human LINGO2 shares 97.9% amino acid (aa) sequence identity with mouse LINGO2.

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Carim-Todd, L., Escarceller, M., Estivill, X., Sumoy, L. LRRN6A/LERN1 (leucine-rich repeat neuronal protein 1), a novel gene with enriched expression in limbic system and neocortex. Europ. J. Neurosci. 18: 3167-3182, 2003.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for LINGO2

Target: LINGO2 (Leucine Rich Repeat and Ig Domain Containing 2 (LINGO2))

Alternative Name: LINGO2 (LINGO2 Products)

Background: Leucine rich repeat and Ig domain containing 2 is a protein that in humans is encoded by the LINGO2 gene. LINGO-2 (LRR and Ig domain-containing, Nogo Receptor-interacting protein 2, also LRRN6C and LERN3), is a member of the LRR transmembrane (TM) protein family. LINGO-2 is thought to function outside the CNS with little involvement by p75/NgR1. The human LINGO-2 precursor is a 606 amino acid (aa) type I TM protein that contains a large extracellular domain and a short cytoplasmic tail. The human LINGO-2 precursor is 99 % and 98 % aa identical to dog and mouse LINGO-2, respectively.

Molecular Weight: 68 kDa

Gene ID: 158038

UniProt: Q7L985