SRR antibody (AA 3-283)

Catalog No. ABIN7601183

This anti-SRR antibody is a Rabbit Polyclonal antibody detecting SRR in WB, IHC, ELISA, FACS, IF, IP and ICC. Suitable for Human, Rat and Mouse.

Quick Overview for SRR antibody (AA 3-283) (ABIN7601183)

Target: SRR (Serine Racemase (SRR))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SRR antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Product Details anti-SRR Antibody

Binding Specificity: AA 3-283

Purpose: Anti-Serine racemase/SRR Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-Serine racemase/SRR Antibody Picoband® (ABIN7601183). Tested in ELISA, Flow Cytometry, IP, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Serine racemase/SRR recombinant protein (Position: A3-E283).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry, 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Immunoprecipitation, 0.5-2 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. De Miranda, J., Santoro, A., Engelender, S., Wolosker, H. Human serine racemase: molecular cloning, genomic organization and functional analysis. Gene 256: 183-188, 2000. 2. Henneberger, C., Papouin, T., Oliet, S. H. R., Rusakov, D. A. Long-term potentiation depends on release of D-serine from astrocytes. Nature 463: 232-236, 2010. 3. Labrie, V., Fukumura, R., Rastogi, A., Fick, L. J., Wang, W., Boutros, P. C., Kennedy, J. L., Semeralul, M. O., Lee, F. H., Baker, G. B., Belsham, D. D., Barger, S. W., Gondo, Y., Wong, A. H. C., Roder, J. C. Serine racemase is associated with schizophrenia susceptibility in humans and in a mouse model. Hum. Molec. Genet. 18: 3227-3243, 2009.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for SRR

Target: SRR (Serine Racemase (SRR))

Alternative Name: SRR

Background:

Synonyms: Dermatopontin, Tyrosine-rich acidic matrix protein, TRAMP, DPT

Tissue Specificity: Expressed in fibroblasts, heart, skeletal muscle, brain and pancreas. Expressed at an intermediate level in lung and kidney, and at a low level in liver and placenta. Expressed at a lower level in fibroblasts from hypertrophic scar lesional skin and in fibroblasts from patients with systemic sclerosis than in normal skin fibroblasts.

Background: SRR(serine racemase) is a 37 kDa protein and belongs to the serine/threonine dehydratase family. It plays a role in neuronal activity and a potential biological role in the regulation of N-methyl-D-aspartate (NMDA) receptor activity in these peripheral organs as well. SRR catalyzes the racemization between l- and d-serine.

Molecular Weight: 37 kDa

Gene ID: 63826