MSRB3 antibody (AA 30-170)

Catalog No. ABIN7601211

Product Details anti-MSRB3 Antibody

Target: MSRB3 (Methionine Sulfoxide Reductase B3 (MSRB3))

Binding Specificity: AA 30-170

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MSRB3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purpose: Anti-MSRB3 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-MSRB3 Antibody Picoband® (ABIN7601211). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human MSRB3 recombinant protein (Position: A30-D170).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Ahmed, Z. M., Yousaf, R., Lee, B. C., Khan, S. N., Lee, S., Lee, K., Husnain, T., Rehman, A. U., Bonneux, S., Ansar, M., Ahmad, W., Leal, S. M., Gladyshev, V. N., Belyantseva, I. A., Van Camp, G., Riazuddin, S., Friedman, T. B., Riazuddin, S. Functional null mutations of MSRB3 encoding methionine sulfoxide reductase are associated with human deafness DFNB74. Am. J. Hum. Genet. 88: 19-29, 2011. 2. Hartz, P. A. Personal Communication. Baltimore, Md. 2/1/2011. 3. Kim, H.-Y., Gladyshev, V. N. Characterization of mouse endoplasmic reticulum methionine-R-sulfoxide reductase. Biochem. Biophys. Res. Commun. 320: 1277-1283, 2004.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for MSRB3

Target: MSRB3 (Methionine Sulfoxide Reductase B3 (MSRB3))

Alternative Name: MSRB3 (MSRB3 Products)

Background:

Synonyms: Pancreatic secretory granule membrane major glycoprotein GP2, Pancreatic zymogen granule membrane protein GP-2, Gp2

Tissue Specificity: Expressed in all tissues tested including, liver, heart, adipose tissue, mammary gland, testes, ovary, brain, kidney and muscle. Highest levels in liver.

Background: The protein encoded by this gene catalyzes the reduction of methionine sulfoxide to methionine. This enzyme acts as a monomer and requires zinc as a cofactor. Several transcript variants encoding two different isoforms have been found for this gene. One of the isoforms localizes to mitochondria while the other localizes to endoplasmic reticula.

Molecular Weight: 21 kDa

Gene ID: 253827