KDM4A antibody (AA 379-1064)
Quick Overview for KDM4A antibody (AA 379-1064) (ABIN7601534)
Target
See all KDM4A AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 379-1064
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Purpose
- Anti-JHDM3A/JMJD2A/KDM4A Antibody
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Cross-Reactivity (Details)
- No cross-reactivity with other proteins.
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Characteristics
- Anti-JHDM3A/JMJD2A/KDM4A Antibody (ABIN7601534). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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Purification
- Immunogen affinity purified.
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Immunogen
- E.coli-derived human JHDM3A/JMJD2A/KDM4A recombinant protein (Position: D379-E1064).
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Isotype
- IgG
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Application Notes
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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Storage
- 4 °C,-20 °C
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Storage Comment
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- KDM4A (Lysine (K)-Specific Demethylase 4A (KDM4A))
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Alternative Name
- KDM4A
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Background
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Synonyms: gasdermin D, gasdermin-D
Tissue Specificity: Brain, placental, and gut tissues.
Background: Lysine-specific demethylase 4A is an enzyme that in humans is encoded by the KDM4A gene. This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein containing a JmjN domain, a JmjC domain, a JD2H domain, two TUDOR domains, and two PHD-type zinc fingers. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form, and as a transcriptional repressor.
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Molecular Weight
- 150 kDa
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Gene ID
- 9682
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UniProt
- O75164
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Pathways
- Warburg Effect
Target
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