LIPC antibody (AA 39-494)

Catalog No. ABIN7601582

This anti-LIPC antibody is a Rabbit Polyclonal antibody detecting LIPC in WB, IHC, ELISA, ICC and IF. Suitable for Human and Rat.

Quick Overview for LIPC antibody (AA 39-494) (ABIN7601582)

Target: LIPC (Lipase, Hepatic (LIPC))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LIPC antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Product Details anti-LIPC Antibody

Binding Specificity: AA 39-494

Purpose: Anti-LIPC Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-LIPC Antibody Picoband® (ABIN7601582). Tested in ELISA, IF, IHC, ICC, WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived rat LIPC recombinant protein (Position: E39-D494).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Rat
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Rat
Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
ELISA, 0.1-0.5 μg/mL,
1. Ameis, D., Stahnke, G., Kobayashi, J., McLean, J., Lee, G., Buscher, M., Schotz, M. C., Will, H. Isolation and characterization of the human hepatic lipase gene. J. Biol. Chem. 265: 6552-6555, 1990. 2. Brown, R. J., Gauthier, A., Parks, R. J., McPherson, R., Sparks, D. L., Schultz, J. R., Yao, Z. Severe hypoalphalipoproteinemia in mice expressing human hepatic lipase deficient in binding to heparan sulfate proteoglycan. J. Biol. Chem. 279: 42403-42409, 2004. 3. Cai, S.-J., Wong, D. M., Chen, S.-H., Chan, L. Structure of the human hepatic triglyceride lipase gene. Biochemistry 28: 8966-8971, 1989.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for LIPC

Target: LIPC (Lipase, Hepatic (LIPC))

Alternative Name: Lipc

Background:

Synonyms: Hepatic triacylglycerol lipase, HL, Hepatic lipase, Lipase member C, Lipc

Background: Hepatic lipase (HL), also called hepatic triglyceride lipase (HTGL) or LIPC (for "lipase, hepatic"), is a form of lipase, catalyzing the hydrolysis of triacylglyceride. It is mapped to 8q24. LIPC encodes hepatic triglyceride lipase, which is expressed in liver. LIPC has the dual functions of triglyceride hydrolase and ligand/bridging factor for receptor-mediated lipoprotein uptake.

Molecular Weight: 56 kDa

Gene ID: 24538

UniProt: P07867

Pathways: Lipid Metabolism