APOA1BP antibody (AA 46-288)

Catalog No. ABIN7601798

This anti-APOA1BP antibody is a Rabbit Polyclonal antibody detecting APOA1BP in WB, IHC, ELISA and FACS. Suitable for Human, Mouse and Rat.

Quick Overview for APOA1BP antibody (AA 46-288) (ABIN7601798)

Target: APOA1BP (Apolipoprotein A-I Binding Protein (APOA1BP))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This APOA1BP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

Product Details anti-APOA1BP Antibody

Binding Specificity: AA 46-288

Purpose: Anti-NAXE Antibody Picoband®

Characteristics: Anti-NAXE Antibody Picoband® (ABIN7601798). Tested in WB, IHC, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human NAXE recombinant protein (Position: R46-Q288). Human NAXE shares 93% and 94.2% amino acid (aa) sequence identity with mouse and rat NAXE, respectively.

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry, 2-5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Fang, L., Choi, S.-H., Baek, J. S., Liu, C., Almazan, F., Ulrich, F., Wiesner, P., Taleb, A., Deer, E., Pattison, J., Torres-Vazquez, J., Li, A. C., Miller, Y. I. Control of angiogenesis by AIBP-mediated cholesterol efflux. Nature 498: 118-122, 2013. 2. Kremer, L. S., Danhauser, K., Herebian, D., Ramadza, D. P., Piekutowska-Abramczuk, D., Seibt, A., Muller-Felber, W., Haack T. B., Ploski, R., Lohmeier, K., Schneider, D., Klee, D., and 10 others. NAXE mutations disrupt the cellular NAD(P)HX repair system and cause a lethal neurometabolic disorder of early childhood. Am. J. Hum. Genet. 99: 894-902, 2016. 3. Marbaix, A. Y., Tyteca, D., Niehaus, T. D., Hanson, A. D., Linster, C. L., Van Schaftingen, E. Occurrence and subcellular distribution of the NAD(P)HX repair system in mammals. Biochem. J. 460: 49-58, 2014.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for APOA1BP

Target: APOA1BP (Apolipoprotein A-I Binding Protein (APOA1BP))

Alternative Name: NAXE

Background: Apolipoprotein A-I-binding protein also known as APOA1BP is a protein that in humans is encoded by the APOA1BP gene. The product of this gene interacts with apolipoprotein A-I (apoA-I), the major apolipoprotein of high-density lipoproteins (HDLs). It is secreted into some bodily fluids, and its synthesis and secretion are stimulated in vitro by incubating cells with apoA-I. The human genome contains related pseudogenes.

Molecular Weight: 26 kDa

Gene ID: 128240