SERPINA7 antibody (AA 55-389)

Catalog No. ABIN7602019

The Rabbit Polyclonal anti-SERPINA7 antibody has been validated for WB, IHC, ELISA and FACS. It is suitable to detect SERPINA7 in samples from Human.

Quick Overview for SERPINA7 antibody (AA 55-389) (ABIN7602019)

Target: SERPINA7 (Serpin Family A Member 7 (SERPINA7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SERPINA7 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

Product Details anti-SERPINA7 Antibody

Binding Specificity: AA 55-389

Purpose: Anti-Thyroxine Binding Globulin/SERPINA7 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-Thyroxine Binding Globulin/SERPINA7 Antibody Picoband® (ABIN7602019). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Thyroxine Binding Globulin/SERPINA7 recombinant protein (Position: R55-R389).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Bertenshaw, R., Takeda, K., Refetoff, S. Sequencing of the variant thyroxine-binding globulin (TBG)-Quebec reveals two nucleotide substitutions. Am. J. Hum. Genet. 48: 741-744, 1991. 2. Buchanan, B. D., Hagen, G. A. Elevated thyroxine-binding globulin with X chromosome linked inheritance. Clin. Endocr. 11: 665-669, 1979. 3. Burr, W. A., Ramsden, D. B., Hoffenberg, R. Hereditary abnormalities of thyroxine-binding globulin concentration: a study of 19 kindreds with inherited increase or decrease of thyroxine-binding globulin. Quart. J. Med. 49: 295-313, 1980.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for SERPINA7

Target: SERPINA7 (Serpin Family A Member 7 (SERPINA7))

Alternative Name: SERPINA7

Background:

Synonyms: CD3 antigen, epsilon polypeptide, CD3e molecule, Cd3e, Cd3e_predicted, rCG_58471

Background: Thyroxine-binding globulin (TBG) is a globulin protein that in humans is encoded by the SERPINA7 gene. There are three proteins including thyroxine-binding globulin (TBG), transthyretin and albumin responsible for carrying the thyroid hormones thyroxine (T4) and 3,5,3'-triiodothyronine (T3) in the bloodstream. This gene encodes the major thyroid hormone transport protein, TBG, in serum. It belongs to the serpin family in genomics, but the protein has no inhibitory function like many other members of the serpin family. Mutations in this gene result in TGB deficiency, which has been classified as partial deficiency, complete deficiency, and excess, based on the level of serum TBG. Alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of these variants has not been determined.

Molecular Weight: 50 kDa

Gene ID: 6906

UniProt: P05543

Pathways: Hormone Transport