IGSF11 antibody (AA 69-378)

Catalog No. ABIN7602301

The Rabbit Polyclonal anti-IGSF11 antibody has been validated for WB and ELISA. It is suitable to detect IGSF11 in samples from Human, Mouse and Rat.

Quick Overview for IGSF11 antibody (AA 69-378) (ABIN7602301)

Target: IGSF11 (Immunoglobulin Superfamily, Member 11 (IGSF11))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IGSF11 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-IGSF11 Antibody

Binding Specificity: AA 69-378

Purpose: Anti-IGSF11 Antibody Picoband®

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Anti-IGSF11 Antibody Picoband® (ABIN7601946). Tested in WB, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human IGSF11 recombinant protein (Position: Q69-R378). Human IGSF11 shares 91.3% and 91% amino acid (aa) sequence identity with mouse and rat IGSF11, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Katoh, M., Katoh, M. IGSF11 gene, frequently up-regulated in intestinal-type gastric cancer, encodes adhesion molecule homologous to CXADR, FLJ22415 and ESAM. Int. J. Oncol. 23: 525-531, 2003. 2. Suzu, S., Hayashi, Y., Harumi, T., Nomaguchi, K., Yamada, M., Hayasawa, H., Motoyoshi, K. Molecular cloning of a novel immunoglobulin superfamily gene preferentially expressed by brain and testis. Biochem. Biophys. Res. Commun. 296: 1215-1221, 2002. 3. Wang, J., Wu, G., Manick, B., Hernandez, V., Renelt, M., Erickson, C., Guan, J., Singh, R., Rollins, S., Solorz, A., Bi, M., Li, J., Grabowski, D., Dirkx, J., Tracy, C., Stuart, T., Ellinghuysen, C., Desmond, D., Foster, C., Kalabokis, V. VSIG-3 as a ligand of VISTA inhibits human T-cell function. Immunology 156: 74-85, 2019.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for IGSF11

Target: IGSF11 (Immunoglobulin Superfamily, Member 11 (IGSF11))

Alternative Name: IGSF11

Background:

Synonyms: 70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70(S6K) alpha antibody, p70(S6K)-alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70 kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody

Tissue Specificity: Expressed in all tissues.

Background: IGSF11 is an immunoglobulin (Ig) superfamily member that is preferentially expressed in brain and testis. It shares significant homology with coxsackievirus and adenovirus receptor (CXADR, MIM 602621) and endothelial cell-selective adhesion molecule (ESAM).

Molecular Weight: 50 kDa

Gene ID: 152404