WDR36 antibody (AA 74-865)

Catalog No. ABIN7602409

Product Details anti-WDR36 Antibody

Target: WDR36 (WD Repeat Domain 36 (WDR36))

Binding Specificity: AA 74-865

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WDR36 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (IF)

Purpose: Anti-WDR36 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-WDR36 Antibody Picoband® (ABIN7602409). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human WDR36 recombinant protein (Position: R74-D865).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Bernstein, K. A., Gallagher, J. E. G., Mitchell, B. M., Granneman, S., Baserga, S. J. The small-subunit processome is a ribosome assembly intermediate. Eukaryotic Cell 3: 1619-1626, 2004. 2. Fingert, J. H., Alward, W. L. M., Kwon, Y. H., Shankar, S. P., Andorf, J. L., Mackey, D. A., Sheffield, V. C., Stone, E. M. No association between variations in the WDR36 gene and primary open-angle glaucoma. Arch. Ophthal. 125: 434-436, 2007. 3. Footz, T. K., Johnson, J. L., Dubois, S., Boivin, N., Raymond, V., Walter, M. A. Glaucoma-associated WDR36 variants encode functional defects in a yeast model system. Hum. Molec. Genet. 18: 1276-1287, 2009.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for WDR36

Target: WDR36 (WD Repeat Domain 36 (WDR36))

Alternative Name: WDR36 (WDR36 Products)

Background:

Synonyms: Protein phosphatase 1 regulatory subunit 14A,17 kDa PKC-potentiated inhibitory protein of PP1,Protein kinase C-potentiated inhibitor protein of 17 kDa,CPI-17,PPP1R14A,CPI17, PPP1INL,

Tissue Specificity: Isoform 1 is detected in aorta and testis. Isoform 2 is detected in aorta. .

Background: WD repeat-containing protein 36 is a protein that in humans is encoded by the WDR36 gene. This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Mutations in this gene have been associated with adult-onset primary open-angle glaucoma (POAG).

Molecular Weight: 105 kDa

Gene ID: 134430

Pathways: Regulation of Cell Size