RPRD1A antibody (AA 76-235)

Catalog No. ABIN7602422

This anti-RPRD1A antibody is a Rabbit Polyclonal antibody detecting RPRD1A in ELISA, WB, IF, ICC, IHC and FACS. Suitable for Human, Mouse and Rat.

Quick Overview for RPRD1A antibody (AA 76-235) (ABIN7602422)

Target: RPRD1A (Regulation of Nuclear Pre-mRNA Domain Containing 1A (RPRD1A))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RPRD1A antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Product Details anti-RPRD1A Antibody

Binding Specificity: AA 76-235

Purpose: Anti-P15RS/RPRD1A Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-P15RS/RPRD1A Antibody Picoband® (ABIN7602422). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human P15RS/RPRD1A recombinant protein (Position: E76-D235).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry, 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Liu, J., Liu, H., Zhang, X., Gao, P., Wang, J., Hu, Z. Identification and characterization of P15RS, a novel P15(INK4B)-related gene on G1/S progression. Biochem. Biophys. Res. Commun. 299: 880-885, 2002. 2. Ni, Z., Olsen, J. B., Guo, X., Zhong, G., Ruan, E. D., Marcon, E., Young, P., Guo, H., Li, J., Moffat, J., Emili, A., Greenblatt, J. F. Control of the RNA polymerase II phosphorylation state in promoter regions by CTD interaction domain-containing proteins RPRD1A and RPRD1B. Transcription 2: 237-242, 2011.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for RPRD1A

Target: RPRD1A (Regulation of Nuclear Pre-mRNA Domain Containing 1A (RPRD1A))

Alternative Name: RPRD1A

Background:

Synonyms: Protein NDRG3,N-myc downstream-regulated gene 3 protein,NDRG3,

Tissue Specificity: Ubiquitous. Highly expressed in brain. .

Background: This gene encodes a cell-cycle and transcription regulatory protein. The encoded protein interacts with the cell cycle inhibitor cyclin-dependent kinase 4 inhibitor B and may function as a negative regulator of G(1)/S phase progression. This protein also forms homo- and hetrodimers with the protein, regulation of nuclear pre-mRNA domain-containing protein 1B, to form a scaffold that interacts with the C-terminal domain of RNA polymerase II subunit B1 and regulates several aspects of transcription. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 16.

Molecular Weight: 36 kDa

Gene ID: 55197

UniProt: Q96P16