PCCB antibody (AA 83-539)

Catalog No. ABIN7602549

This Rabbit Polyclonal antibody specifically detects PCCB in WB, ELISA, IHC, FACS and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for PCCB antibody (AA 83-539) (ABIN7602549)

Target: PCCB (Propionyl CoA Carboxylase beta Polypeptide (PCCB))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCCB antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF)

Product Details anti-PCCB Antibody

Binding Specificity: AA 83-539

Purpose: Anti-PCCB Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-PCCB Antibody (ABIN7602549). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PCCB recombinant protein (Position: D83-L539).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for PCCB

Target: PCCB (Propionyl CoA Carboxylase beta Polypeptide (PCCB))

Alternative Name: PCCB

Background:

Synonyms: Interleukin-3 receptor subunit alpha, IL-3 receptor subunit alpha, IL-3R subunit alpha, IL-3R-alpha, IL-3RA, CD123, IL3RA, IL3R

Tissue Specificity: Brain.

Background: The protein encoded by this gene is a subunit of the propionyl-CoA carboxylase (PCC) enzyme, which is involved in the catabolism of propionyl-CoA. PCC is a mitochondrial enzyme that probably acts as a dodecamer of six alpha subunits and six beta subunits. This gene encodes the beta subunit of PCC. Defects in this gene are a cause of propionic acidemia type II (PA-2). Multiple transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 55 kDa

Gene ID: 5096

UniProt: P05166

Pathways: Monocarboxylic Acid Catabolic Process