IFITM1 antibody (C-Term)

Catalog No. ABIN7602829

The Rabbit Polyclonal anti-IFITM1 antibody has been validated for WB. It is suitable to detect IFITM1 in samples from Human.

Quick Overview for IFITM1 antibody (C-Term) (ABIN7602829)

Target: IFITM1 (Interferon-Induced Transmembrane Protein 1 (IFITM1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IFITM1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-IFITM1 Antibody

Binding Specificity: C-Term

Purpose: Anti-IFITM1 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-IFITM1 Antibody Picoband® (ABIN7602829). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human IFITM1.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human
1. Tanaka, S. S., Yamaguchi, Y. L., Tsoi, B., Lickert, H., Tam, P. P. L. : IFITM/Mil/Fragilis family proteins IFITM1 and IFITM3 play distinct roles in mouse primordial germ cell homing and repulsion. Dev. Cell 9: 745-756, 2005. 2. Deblandre, G. A., Marinx, O. P., Evans. S. S., Majjaj, S., Leo, O., Caput, D., Huez, G. A., Wathelet, M. G. : Expression cloning of an interferon-inducible 17- kDa membrane protein implicated in the control of cell growth. J. Biol. Chem. 270: 23860-23866, 1995.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for IFITM1

Target: IFITM1 (Interferon-Induced Transmembrane Protein 1 (IFITM1))

Alternative Name: IFITM1

Background:

Synonyms: Cadherin-5, Vascular endothelial cadherin, VE-cadherin, CD144, Cdh5

Tissue Specificity: Endothelial tissues and brain.

Background: Interferon-induced Transmembrane Protein 1 (IFITM1), also called Interferon-induced Protein 17 (IFI17). IFITM1 activity is required for primordial germ cells (PGCs) transit from the mesoderm into the endoderm, and that it appears to act via a repulsive mechanism, such that PGCs avoid Ifitm1-expressing tissues. It is mapped to Chr.11 and belongs to the family of interferon-induced transmembrane proteins (Ifitm/mil/fragilis), which encodes cell surface proteins that may modulate cell adhesion and influence cell differentiation. Interferon-inducible membrane proteins of approximately 17 kDa have been suggested to play a role in the antiproliferative activity of interferons based on their pattern of induction in interferon-sensitive and -resistant cell lines and the ability of a membrane fraction enriched in 17- kDa proteins to inhibit cell growth.

Molecular Weight: 17 kDa

Gene ID: 8519

UniProt: P13164