LPP antibody (C-Term)

Catalog No. ABIN7602831

This Rabbit Polyclonal antibody specifically detects LPP in WB, IHC and IF. It exhibits reactivity toward Human, Mouse, Rat and Monkey.

Quick Overview for LPP antibody (C-Term) (ABIN7602831)

Target: LPP (Lipoma-preferred partner (LPP))

Reactivity: Human, Mouse, Rat, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LPP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-LPP Antibody

Binding Specificity: C-Term

Purpose: Anti-LPP Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-LPP Antibody Picoband® (ABIN7602831). Tested in IF, IHC, WB applications. This antibody reacts with Human, Monkey, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human LPP, which shares 100% and 94.7% amino acid (aa) sequence identity with mouse and rat LPP, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat, Monkey
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Rat
Immunofluorescence, 5 μg/mL, Human
1. Daheron, L., Veinstein, A., Brizard, F., Drabkin, H., Lacotte, L., Guilhot, F., Larsen, C. J., Brizard, A., Roche, J. Human LPP gene is fused to MLL in a secondary acute leukemia with a t(3,11)(q28,q23). Genes Chromosomes Cancer 31: 382-389, 2001. 2. Petit, M. M. R., Mols, R., Schoenmakers, E. F. P. M., Mandahl, N., Van de Ven, W. J. M. LPP, the preferred fusion partner gene of HMGIC in lipomas, is a novel member of the LIM protein gene family. Genomics 36: 118-129, 1996.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for LPP

Target: LPP (Lipoma-preferred partner (LPP))

Alternative Name: LPP

Background:

Synonyms: Lipoma-preferred partner, LIM domain-containing preferred translocation partner in lipoma, LPP

Tissue Specificity: Expressed in a wide variety of tissues but no or very low expression in brain and peripheral leukocytes.

Background: LPP (Lim Domain-Containing Preferred Translocation Partner in Lipoma), is a protein that in humans is encoded by the LPP gene. Petit et al. (1996) commented that the LPP-encoded protein should be classified as a novel member of the group 3 proteins of the LIM protein gene family. By partial cDNA cloning, Petit et al. (1996) established features of the genetic organization of LPP. The gene was found to span a genomic region of over 400 kb. By FISH and Southern blot analyses, Daheron et al. (2001) identified a rearrangement in the mixed lineage leukemia gene due to a novel t (3,11) (q28,q23) translocation in a patient who developed acute myeloid leukemia of the M5 type 3 years after treatment for a follicular lymphoma.

Molecular Weight: 80 kDa

Gene ID: 4026

UniProt: Q93052