S100A14 antibody (C-Term)

Catalog No. ABIN7602920

Product Details anti-S100A14 Antibody

Target: S100A14 (S100 Calcium Binding Protein A14 (S100A14))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This S100A14 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Purpose: Anti-S100A14 Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-A14 Antibody Picoband® (ABIN7602920). Tested in IHC applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human S100A14, which shares 93.8% amino acid (aa) sequence identity with mouse S100A14.

Isotype: IgG

Application Details

Application Notes: Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
1. Adam, P. J., Boyd, R., Tyson, K. L., Fletcher, G. C., Stamps, A., Hudson, L., Poyser, H. R., Redpath, N., Griffiths, M., Steers, G., Harris, A. L., Patel, S., Berry, J., Loader, J. A., Townsend, R. R., Daviet, L., Legrain, P., Parekh, R., Terrett, J. A. Comprehensive proteomic analysis of breast cancer cell membranes reveals unique proteins with potential roles in clinical cancer. J. Biol. Chem. 278: 6482-6489, 2003. 2. Chen, H., Yu, D., Luo, A., Tan, W., Zhang, C., Zhao, D., Yang, M., Liu, J., Lin, D., Liu, Z. Functional role of S100A14 genetic variants and their association with esophageal squamous cell carcinoma. Cancer Res. 69: 3451-3457, 2009. 3. Pietas, A., Schluns, K., Marenholz, I., Schafer, B. W., Heizmann, C. W., Petersen, I. Molecular cloning and characterization of the human S100A14 gene encoding a novel member of the S100 family. Genomics 79: 513-522, 2002.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for S100A14

Target: S100A14 (S100 Calcium Binding Protein A14 (S100A14))

Alternative Name: S100A14 (S100A14 Products)

Background:

Synonyms: ELAV-like protein 2, ELAV-like neuronal protein 1, Hu-antigen B, HuB, Nervous system-specific RNA-binding protein Hel-N1, ELAVL2, HUB

Tissue Specificity: Brain, neural-specific.

Background: S100 calcium binding protein A14 (S100A14) is a protein that in humans is encoded by the S100A14 gene. This gene encodes a member of the S100 protein family which contains an EF-hand motif and binds calcium. The gene is located in a cluster of S100 genes on chromosome 1. Levels of the encoded protein have been found to be lower in cancerous tissue and associated with metastasis suggesting a tumor suppressor function.

Molecular Weight: 18 kDa

Gene ID: 57402

Pathways: Activation of Innate immune Response, S100 Proteins