S100P antibody (C-Term)

Catalog No. ABIN7602921

This Rabbit Polyclonal antibody specifically detects S100P in WB, IF, ICC and FACS. It exhibits reactivity toward Human.

Quick Overview for S100P antibody (C-Term) (ABIN7602921)

Target: S100P (S100 Calcium Binding Protein P (S100P))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This S100P antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Product Details anti-S100P Antibody

Binding Specificity: C-Term

Purpose: Anti-S100P Antibody Picoband®

Characteristics: Anti-P Antibody Picoband® (ABIN7602921). Tested in WB, ICC/IF, Flow Cytometry applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human S100P.

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
1. Becker, T., Gerke, V., Kube, E., Weber, K. S100P, a novel Ca(2+)-binding protein from human placenta: cDNA cloning, recombinant protein expression and Ca(2+) binding properties. Europ. J. Biochem. 207: 541-547, 1992. 2. Dowen, S. E., Crnogorac-Jurcevic, T., Gangeswaran, R., Hansen, M., Eloranta, J. J., Bhatka, V., Brentnall, T. A., Luttges, J., Kloppel, G., Lemoine, N. R. Expression of S100P and its novel binding partner S100PBPR in early pancreatic cancer. Am. J. Path. 166: 81-92, 2005. 3. Schafer, B. W., Wicki, R., Engelkamp, D., Mattei, M.-G., Heizmann, C. W. Isolation of a YAC clone covering a cluster of nine S100 genes on human chromosome 1q21: rationale for a new nomenclature of the S100 calcium-binding protein family. Genomics 25: 638-643, 1995.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for S100P

Target: S100P (S100 Calcium Binding Protein P (S100P))

Alternative Name: S100P

Background: S100 calcium-binding protein P (S100P) is a protein that in humans is encoded by the S100P gene. The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21, however, this gene is located at 4p16. This protein, in addition to binding Ca2+, also binds Zn2+ and Mg2+. This protein may play a role in the etiology of prostate cancer.

Molecular Weight: 14 kDa

Gene ID: 6286

UniProt: P25815

Pathways: Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades, S100 Proteins