FGL1 antibody (Middle Region)

Catalog No. ABIN7603048

The Rabbit Polyclonal anti-FGL1 antibody has been validated for WB. It is suitable to detect FGL1 in samples from Human, Mouse and Rat.

Quick Overview for FGL1 antibody (Middle Region) (ABIN7603048)

Target: FGL1 (Fibrinogen-Like 1 (FGL1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FGL1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FGL1 Antibody

Binding Specificity: Middle Region

Purpose: Anti-FGL1 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-FGL1 Antibody Picoband® (ABIN7603048). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human FGL1.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
1. Gross, M. B. Personal Communication. Baltimore, Md. 2/22/2019. 2. Hara, H., Yoshimura, H., Uchida, S., Toyoda, Y., Aoki, M., Sakai, Y., Morimoto, S., Shiokawa, K. Molecular cloning and functional expression analysis of a cDNA for human hepassocin, a liver-specific protein with hepatocyte mitogenic activity. Biochim. Biophys. Acta 1520: 45-53, 2001. 3. Wang, J., Sanmamed, M. F., Datar, I., Su, T. T., Ji, L., Sun, J., Chen, L., Chen, Y., Zhu, G., Yin, W., Zheng, L., Zhou, T., and 9 others. Fibrinogen-like protein 1 is a major immune inhibitory ligand of LAG-3. Cell 176: 334-347, 2019.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for FGL1

Target: FGL1 (Fibrinogen-Like 1 (FGL1))

Alternative Name: FGL1

Background:

Synonyms: FGL1, HFREP1, Fibrinogen-like protein 1, HP-041, Hepassocin, HPS, Hepatocyte-derived fibrinogen-related protein 1, HFREP-1, Liver fibrinogen-related protein 1, LFIRE-1

Background: Fibrinogen-like 1 is a member of the fibrinogen family. This protein is homologous to the carboxy terminus of the fibrinogen beta- and gamma- subunits which contains the four conserved cysteines of fibrinogens and fibrinogen related proteins. However, this protein lacks the platelet-binding site, cross-linking region and a thrombin-sensitive site which are necessary for fibrin clot formation. This protein may play a role in the development of hepatocellular carcinomas. Four alternatively spliced transcript variants encoding the same protein exist for this gene.

Molecular Weight: 36 kDa

Gene ID: 2267

UniProt: Q08830