SFR1 antibody (Middle Region)

Catalog No. ABIN7603090

Product Details anti-SFR1 Antibody

Target: SFR1 (SWI5-Dependent Recombination Repair 1 (SFR1))

Binding Specificity: Middle Region

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SFR1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Purpose: Anti-SFR1 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-SFR1 Antibody Picoband® (ABIN7603090). Tested in Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human SFR1.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
1. Akamatsu, Y., Jasin, M. Role for the mammalian Swi5-Sfr1 complex in DNA strand break repair through homologous recombination. PLoS Genet. 6: e1001160, 2010. Note: Electronic Article. 2. Feng, Y., Singleton, D., Guo, C., Gardner, A., Pakala, S., Kumar, R., Jensen, E., Zhang, J., Khan, S. DNA homologous recombination factor SFR1 physically and functionally interacts with estrogen receptor alpha. PLoS One 8: e68075, 2013. Note: Electronic Article. 3. Hartz, P. A. Personal Communication. Baltimore, Md. 8/17/2015.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for SFR1

Target: SFR1 (SWI5-Dependent Recombination Repair 1 (SFR1))

Alternative Name: SFR1 (SFR1 Products)

Background:

Synonyms: Trem-like transcript 1 protein,TLT-1,Triggering receptor expressed on myeloid cells-like protein 1,TREML1,TLT1,UNQ1825/PRO3438,

Tissue Specificity: Detected in platelets, monocytic leukemia and in T-cell leukemia. .

Background: SFR1 is a component of the SWI5-SFR1 complex, a complex required for double-strand break repair via homologous recombination.

Molecular Weight: 22 kDa

Gene ID: 119392