ACP2 antibody (N-Term)

Catalog No. ABIN7603192

The Rabbit Polyclonal anti-ACP2 antibody has been validated for WB. It is suitable to detect ACP2 in samples from Human, Rat and Mouse.

Quick Overview for ACP2 antibody (N-Term) (ABIN7603192)

Target: ACP2 (Acid Phosphatase 2, Lysosomal (ACP2))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACP2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ACP2 Antibody

Binding Specificity: N-Term

Purpose: Anti-ACP2 Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-ACP2 Antibody (ABIN7603192). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human ACP2, which shares 100% and 96.4% amino acid (aa) sequence identity with mouse and rat ACP2, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for ACP2

Target: ACP2 (Acid Phosphatase 2, Lysosomal (ACP2))

Alternative Name: ACP2

Background:

Synonyms: AP-2 complex subunit beta,AP105B,Adaptor protein complex AP-2 subunit beta,Adaptor-related protein complex 2 subunit beta,Beta-2-adaptin,Beta-adaptin,Clathrin assembly protein complex 2 beta large chain,Plasma membrane adaptor HA2/AP2 adaptin beta subunit,AP2B1,ADTB2, CLAPB1,

Tissue Specificity: Widely expressed, at a low level, and the highest expression is observed in skeletal muscle and brain. Also detected in fetal liver.

Background: Lysosomal acid phosphatase is an enzyme that in humans is encoded by the ACP2 gene. The protein encoded by this gene belongs to the histidine acid phosphatase family, which hydrolyze orthophosphoric monoesters to alcohol and phosphate. This protein is localized to the lysosomal membrane, and is chemically and genetically distinct from the red cell acid phosphatase. Mice lacking this gene showed multiple defects, including bone structure alterations, lysosomal storage defects, and an increased tendency towards seizures. An enzymatically-inactive allele of this gene in mice showed severe growth retardation, hair-follicle abnormalities, and an ataxia-like phenotype. Alternatively spliced transcript variants have been found for this gene. A C-terminally extended isoform is also predicted to be produced by the use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism.

Molecular Weight: 76 kDa

Gene ID: 53

UniProt: P11117