Acetyl-CoA Carboxylase alpha antibody

Catalog No. ABIN7603882

The Rabbit Monoclonal anti-Acetyl-CoA Carboxylase alpha antibody has been validated for WB and IHC. It is suitable to detect Acetyl-CoA Carboxylase alpha in samples from Human, Mouse and Rat.

Quick Overview for Acetyl-CoA Carboxylase alpha antibody (ABIN7603882)

Target: Acetyl-CoA Carboxylase alpha (ACACA)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Acetyl-CoA Carboxylase alpha antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: EDI-1

Product Details anti-Acetyl-CoA Carboxylase alpha Antibody

Purpose: Anti-Acetyl-CoA Carboxylase Monoclonal Antibody

Characteristics: Anti-Acetyl-CoA Carboxylase Monoclonal Antibody (ABIN7603882). Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human Acetyl-CoA Carboxylase ACC1 a subunit of acetyl-CoA carboxylase (ACC), a multifunctional enzyme system. Catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. Acetyl-CoA carboxylase (ACC) catalyzes the pivotal step of the fatty acid synthesis pathway. The 265 kDa ACC Alpha (ACC1) is the predominant isoform found in liver, adipocytes, and mammary gland, while the 280 kDa ACC Beta (ACC2) is the major isoform in skeletal muscle and heart.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-1:2000
IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Concentration: Lot specific

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Target Details for Acetyl-CoA Carboxylase alpha

Target: Acetyl-CoA Carboxylase alpha (ACACA)

Alternative Name: ACACA

Background:

Synonyms: Heterogeneous nuclear ribonucleoprotein K,hnRNP K,Transformation up-regulated nuclear protein,TUNP,HNRNPK,HNRPK,

Tissue Specificity: Expressed in brain and lymphoblast.

Molecular Weight: 55 kDa

Pathways: AMPK Signaling, Ribonucleoside Biosynthetic Process, Warburg Effect