Caspase 2 antibody

Catalog No. ABIN7604229

This Rabbit Monoclonal antibody specifically detects Caspase 2 in WB. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Caspase 2 antibody (ABIN7604229)

Target: Caspase 2 (CASP2) (Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Caspase 2 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: GDH-3

Product Details anti-Caspase 2 Antibody

Purpose: Anti-Caspase-2 CASP2 Rabbit Monoclonal Antibody

Characteristics: Anti-Caspase-2 CASP2 Rabbit Monoclonal Antibody (ABIN7604229). Tested in WB application. This antibody reacts with Human, Mouse, Rat.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human Caspase-2

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Concentration: Lot specific

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Target Details for Caspase 2

Target: Caspase 2 (CASP2) (Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2))

Alternative Name: CASP2

Background:

Synonyms: Caspase-2,CASP-2,3.4.22.55,Neural precursor cell expressed developmentally down-regulated protein 2,NEDD-2,Protease ICH-1,Caspase-2 subunit p18,Caspase-2 subunit p13,Caspase-2 subunit p12,CASP2,ICH1, NEDD2,

Tissue Specificity: Expressed at higher levels in the embryonic lung, liver and kidney than in the heart and brain. In adults, higher level expression is seen in the placenta, lung, kidney, and pancreas than in the heart, brain, liver and skeletal muscle.

Molecular Weight: 47 kDa

UniProt: P42575

Pathways: Apoptosis, Caspase Cascade in Apoptosis, Neurotrophin Signaling Pathway