CUBN antibody

Catalog No. ABIN7604532

This Rabbit Monoclonal antibody specifically detects CUBN in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for CUBN antibody (ABIN7604532)

Target: CUBN (Cubilin (Intrinsic Factor-Cobalamin Receptor) (CUBN))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CUBN antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: GA-3

Product Details anti-CUBN Antibody

Purpose: Anti-Cubilin CUBN Rabbit Monoclonal Antibody

Characteristics: Anti-Cubilin CUBN Rabbit Monoclonal Antibody (ABIN7604532). Tested in WB, IHC applications. This antibody reacts with Human.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human Cubilin

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000
IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Concentration: Lot specific

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Target Details for CUBN

Target: CUBN (Cubilin (Intrinsic Factor-Cobalamin Receptor) (CUBN))

Alternative Name: CUBN

Background:

Synonyms: Cubilin,460 kDa receptor,Intestinal intrinsic factor receptor,Intrinsic factor-cobalamin receptor,Intrinsic factor-vitamin B12 receptor,CUBN,IFCR,

Tissue Specificity: Expressed in kidney proximal tubule cells, placenta, visceral yolk-sac cells and in absorptive intestinal cells. Expressed in the epithelium of intestine and kidney.

Molecular Weight: 163 kDa

UniProt: O60494

Pathways: Metabolism of Steroid Hormones and Vitamin D, Lipid Metabolism