RAPGEF3 antibody

Catalog No. ABIN7604755

The Rabbit Monoclonal anti-RAPGEF3 antibody has been validated for WB, IF, IHC, ICC and IP. It is suitable to detect RAPGEF3 in samples from Human, Mouse and Rat.

Quick Overview for RAPGEF3 antibody (ABIN7604755)

Target: RAPGEF3 (Rap Guanine Nucleotide Exchange Factor (GEF) 3 (RAPGEF3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This RAPGEF3 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Clone: AEOG-18

Product Details anti-RAPGEF3 Antibody

Purpose: Anti-Epac1 Rabbit Monoclonal Antibody

Characteristics: Anti-Epac1 Rabbit Monoclonal Antibody (ABIN7604755). Tested in WB, IHC, ICC/IF, IP applications. This antibody reacts with Human, Mouse, Rat.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human Epac1 The activation of RaP1 by cAMP is independent of PKA and is mediated by recently discovered family of guanine nucleotide exchange factors (GEFs) called cAMP-GEFs or Epacs. The Epac signaling therefore represents a novel mechanism for cAMP signaling with in the cAMP cascade.

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000
IHC 1:50-200
ICC/IF 1:50-200
IP 1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Concentration: 0.5 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Target Details for RAPGEF3

Target: RAPGEF3 (Rap Guanine Nucleotide Exchange Factor (GEF) 3 (RAPGEF3))

Alternative Name: RAPGEF3

Background:

Synonyms: Fatty acid-binding protein, liver,Fatty acid-binding protein 1,Liver-type fatty acid-binding protein,L-FABP,FABP1,FABPL,

Tissue Specificity: Highly expressed and ubiquitous. Isoform Pin2 predominates.

Molecular Weight: 73 kDa

UniProt: O95398

Pathways: cAMP Metabolic Process