Gelsolin antibody

Catalog No. ABIN7604957

This anti-Gelsolin antibody is a Rabbit Monoclonal antibody detecting Gelsolin in WB, IHC, ICC, FACS and IF. Suitable for Human and Mouse.

Quick Overview for Gelsolin antibody (ABIN7604957)

Target: Gelsolin (GSN)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Gelsolin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: AEHE-7

Product Details anti-Gelsolin Antibody

Purpose: Anti-Gelsolin GSN Rabbit Monoclonal Antibody

Characteristics: Anti-Gelsolin GSN Rabbit Monoclonal Antibody (ABIN7604957). Tested in WB, IHC, ICC/IF, Flow Cytometry applications. This antibody reacts with Human, Mouse.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human Gelsolin.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-1:5000
IHC 1:50-1:200
ICC/IF 1:50-1:200
FC 1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Concentration: Lot specific

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Target Details for Gelsolin

Target: Gelsolin (GSN)

Alternative Name: GSN

Background:

Synonyms: E3 ubiquitin-protein ligase NEDD4-like,6.3.2.-,NEDD4.2,Nedd4-2,NEDD4L,KIAA0439, NEDL3,

Tissue Specificity: Ubiquitously expressed, with highest levels in prostate, pancreas and kidney (PubMed:14615060, PubMed:15496141, PubMed:19664597). Expressed in melanocytes (PubMed:23999003). .

Molecular Weight: 40-48 kDa

UniProt: P06396

Pathways: Caspase Cascade in Apoptosis, Regulation of Actin Filament Polymerization, Autophagy