LGR5 antibody

Catalog No. ABIN7605423

This Rabbit Monoclonal antibody specifically detects LGR5 in WB, FACS and IP. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for LGR5 antibody (ABIN7605423)

Target: LGR5 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This LGR5 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP)

Clone: CHF-12

Product Details anti-LGR5 Antibody

Purpose: Anti-LGR5/GPR49 Rabbit Monoclonal Antibody

Characteristics: Anti-LGR5/GPR49 Rabbit Monoclonal Antibody (ABIN7605423). Tested in WB, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human LGR5/GPR49

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000
IP 1:20
FC 1:20

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Concentration: 0.5 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Target Details for LGR5

Target: LGR5 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5))

Alternative Name: LGR5

Background:

Synonyms: Leucine-rich repeat-containing G-protein coupled receptor 5,G-protein coupled receptor 49,G-protein coupled receptor 67,G-protein coupled receptor HG38,LGR5,GPR49, GPR67,

Tissue Specificity: Expressed in skeletal muscle, placenta, spinal cord, and various region of brain. Expressed at the base of crypts in colonic and small mucosa stem cells. In premalignant cancer expression is not restricted to the cript base. Overexpressed in cancers of the ovary, colon and liver. .

Molecular Weight: 100-110 kDa

UniProt: O75473

Pathways: WNT Signaling