PD-L1 antibody

Catalog No. ABIN7605884

This anti-PD-L1 antibody is a Rabbit Monoclonal antibody detecting PD-L1 in WB and IHC. Suitable for Human, Mouse and Rat.

Quick Overview for PD-L1 antibody (ABIN7605884)

Target: PD-L1 (CD274 (PD-L1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This PD-L1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: IDC-3

Product Details anti-PD-L1 Antibody

Purpose: Anti-PD-L1 (CD274) Rabbit Monoclonal Antibody

Characteristics: Anti-PD-L1 Rabbit Monoclonal Antibody (ABIN7605884). Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human PD-L1 (CD274)

Isotype: IgG

Application Details

Application Notes: WB 1:100-1:500
IHC 1:50-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Concentration: Lot specific

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Target Details for PD-L1

Target: PD-L1 (CD274 (PD-L1))

Alternative Name: CD274

Background:

Synonyms: Programmed cell death 1 ligand 1,PD-L1,PDCD1 ligand 1,Programmed death ligand 1,B7 homolog 1,B7-H1,CD274,CD274,B7H1, PDCD1L1, PDCD1LG1, PDL1,

Tissue Specificity: Highly expressed in the heart, skeletal muscle, placenta and lung. Weakly expressed in the thymus, spleen, kidney and liver. Expressed on activated T- and B-cells, dendritic cells, keratinocytes and monocytes. .

Molecular Weight: 40 kDa

Pathways: Cancer Immune Checkpoints