XBP1 antibody

Catalog No. ABIN7606725

This Rabbit Monoclonal antibody specifically detects XBP1 in WB, IHC, FACS, IF and ICC. It exhibits reactivity toward Human.

Quick Overview for XBP1 antibody (ABIN7606725)

Target: XBP1 (X-Box Binding Protein 1 (XBP1))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This XBP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF), Immunocytochemistry (ICC)

Clone: AAAF-24

Product Details anti-XBP1 Antibody

Purpose: Anti-XBP1 Rabbit Monoclonal Antibody

Characteristics: Anti-XBP1 Rabbit Monoclonal Antibody (ABIN7606725). Tested in WB, IHC, ICC/IF, Flow Cytometry applications. This antibody reacts with Human.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human XBP1

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000
IHC 1:100-1:500
ICC/IF 1:50-1:200
FC 1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Concentration: Lot specific

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Target Details for XBP1

Target: XBP1 (X-Box Binding Protein 1 (XBP1))

Alternative Name: XBP1

Background:

Synonyms: X-box-binding protein 1 ,XBP-1 ,Tax-responsive element-binding protein 5 ,TREB-5 ,X-box-binding protein 1, cytoplasmic form ,X-box-binding protein 1, luminal form ,XBP1 ,TREB5 , XBP2 ,

Tissue Specificity: Expressed in plasma cells in rheumatoid synovium (PubMed:11460154). Over-expressed in primary breast cancer and metastatic breast cancer cells (PubMed:25280941). Isoform 1 and isoform 2 are expressed at higher level in proliferating as compared to confluent quiescent endothelial cells (PubMed:19416856). .

Molecular Weight: 100-110 kDa

UniProt: P17861

Pathways: ER-Nucleus Signaling, Unfolded Protein Response