MAGEA1 antibody (AA 101-200) (Cy5.5)

Catalog No. ABIN728583

Product Details anti-MAGEA1 Antibody (Cy5.5)

Target: MAGEA1 (Melanoma Antigen Family A, 1 (Directs Expression of Antigen MZ2-E) (MAGEA1))

Binding Specificity: AA 101-200

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAGEA1 antibody is conjugated to Cy5.5

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MAGE-1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for MAGEA1

Target: MAGEA1 (Melanoma Antigen Family A, 1 (Directs Expression of Antigen MZ2-E) (MAGEA1))

Alternative Name: MAGE-1 (MAGEA1 Products)

Synonyms: CT1.1 antibody, MAGE1 antibody, Mage-a1 antibody, MAGE family member A1 antibody, melanoma antigen, family A, 1 antibody, MAGEA1 antibody, Magea1 antibody

Background:

Synonyms: CT1.1, MAGE1, Melanoma-associated antigen 1, Antigen MZ2-E, Cancer/testis antigen 1.1, MAGE-1 antigen, MAGEA1, MAGE1A

Background: May be involved in transcriptional regulation through interaction with SNW1 and recruiting histone deactelyase HDAC1. May inhibit notch intracellular domain (NICD) transactivation. May play a role in embryonal development and tumor transformation or aspects of tumor progression. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes.

Gene ID: 4100

UniProt: P43355