MAGEA1 antibody (AA 1-309)

Catalog No. ABIN7159251

Product Details anti-MAGEA1 Antibody

Target: MAGEA1 (Melanoma Antigen Family A, 1 (Directs Expression of Antigen MZ2-E) (MAGEA1))

Binding Specificity: AA 1-309

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAGEA1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Melanoma-associated antigen 1 protein (1-309AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200, IP:1:200-1:2000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for MAGEA1

Target: MAGEA1 (Melanoma Antigen Family A, 1 (Directs Expression of Antigen MZ2-E) (MAGEA1))

Alternative Name: MAGEA1 (MAGEA1 Products)

Synonyms: CT1.1 antibody, MAGE1 antibody, Mage-a1 antibody, MAGE family member A1 antibody, melanoma antigen, family A, 1 antibody, MAGEA1 antibody, Magea1 antibody

Background:

Background: May be involved in transcriptional regulation through interaction with SNW1 and recruiting histone deactelyase HDAC1. May inhibit notch intracellular domain (NICD) transactivation. May play a role in embryonal development and tumor transformation or aspects of tumor progression. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes.

Aliases: Antigen MZ2 E antibody, Antigen MZ2-E antibody, Cancer/testis antigen 1.1 antibody, cancer/testis antigen family 1, member 1 antibody, CT1.1 antibody, MAGA1_HUMAN antibody, MAGE 1 antigen antibody, MAGE-1 antigen antibody, MAGE1 antibody, MAGE1A antibody, MAGEA1 antibody, Melanoma antigen 1 antibody, Melanoma antigen family A 1 (directs expression of antigen MZ2 E) antibody, Melanoma antigen family A 1 antibody, Melanoma antigen MAGE 1 antibody, Melanoma associated antigen 1 antibody, Melanoma associated antigen MZ2 E antibody, Melanoma-associated antigen 1 antibody, MGC9326 antibody

UniProt: P43355