TIM3 antibody

Catalog No. ABIN7640186

The Mouse Monoclonal anti-TIM3 antibody has been validated for WB, IHC, IP and ICC. It is suitable to detect TIM3 in samples from Human.

Quick Overview for TIM3 antibody (ABIN7640186)

Target: TIM3 (TIM 3) (Hepatitis A Virus Cellular Receptor 2 (TIM 3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TIM3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Clone: C9

Product Details anti-TIM3 Antibody

Purpose: Monoclonal Antibody to Hepatitis A Virus Cellular Receptor 2 (HAVCR2)

Specificity: The antibody is a mouse monoclonal antibody raised against HAVCR2. It has been selected for its ability to recognize HAVCR2 in immunohistochemical staining and western blotting.

Purification: Protein A + Protein G affinity chromatography

Immunogen: RPH930Hu01Recombinant Hepatitis A Virus Cellular Receptor 2 (HAVCR2)

Application Details

Application Notes: Western blotting: 0.2-2 μg/mL,Immunohistochemistry: 5-20 μg/mL,Immunocytochemistry: 5-20 μg/mL,Optimal working dilutions must be determined by end user.

Comment:

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.01M PBS, pH 7.4, containing 0.05 % Proclin-300, 50 % glycerol.

Preservative: ProClin, Sodium azide

Precaution of Use: This product contains ProClin and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Target Details for TIM3

Target: TIM3 (TIM 3) (Hepatitis A Virus Cellular Receptor 2 (TIM 3))

Alternative Name: HAVCR2

Background: KIM-3, TIM3, TIMD3, Tim-3, T-cell membrane protein 3, T-cell immunoglobulin mucin receptor 3, T-cell immunoglobulin and mucin domain-containing protein 3

UniProt: Q8TDQ0

Pathways: Regulation of Lipid Metabolism by PPARalpha, Cancer Immune Checkpoints