CCR6 antibody (AA 201-300)

Catalog No. ABIN731093

The Rabbit Polyclonal anti-CCR6 antibody has been validated for ELISA and WB. It is suitable to detect CCR6 in samples from Human and Mouse. There is 1 publication available.

Quick Overview for CCR6 antibody (AA 201-300) (ABIN731093)

Target: CCR6 (Chemokine (C-C Motif) Receptor 6 (CCR6))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCR6 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-CCR6 Antibody

Binding Specificity: AA 201-300

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CCR6

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-CCR6 antibody (ABIN731093)

Kalyanasundaram Bhanumathy, Zhang, Xie, Xu, Tan, Xiang: "Potent immunotherapy against well-established thymoma using adoptively transferred transgene IL-6-engineered dendritic cell-stimulated CD8(+) T-cells with prolonged survival and enhanced cytotoxicity." in: The journal of gene medicine, (2015) (PubMed).

Target Details for CCR6

Target: CCR6 (Chemokine (C-C Motif) Receptor 6 (CCR6))

Alternative Name: CCR6/CD196

Background:

Synonyms: BN-1, DCR2, DRY6, CCR-6, CD196, CKRL3, GPR29, CKR-L3, CMKBR6, GPRCY4, STRL22, CC-CKR-6, C-C CKR-6, C-C chemokine receptor type 6, Chemokine receptor-like 3, G-protein coupled receptor 29, GPR-CY4, LARC receptor, CCR6

Background: Receptor for a C-C type chemokine. Binds to MIP-3-alpha/LARC and subsequently transduces a signal by increasing the intracellular calcium ions level.

Gene ID: 1235

UniProt: P51684

Pathways: cAMP Metabolic Process