Reelin antibody

Catalog No. ABIN731348

The Rabbit Polyclonal anti-Reelin antibody has been validated for IHC (p) and IF (p). It is suitable to detect Reelin in samples from Human, Rat and Mouse.

Quick Overview for Reelin antibody (ABIN731348)

Target: Reelin (RELN)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Reelin antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-Reelin Antibody

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human RELN

Isotype: IgG

Application Details

Application Notes: IHC-P 1:100-500
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C

Expiry Date: 12 months

Target Details for Reelin

Target: Reelin (RELN)

Alternative Name: Reln/Reelin

Background:

Extracellular matrix serine protease that plays a role in layering of neurons in the cerebral cortex and cerebellum. Regulates microtubule function in neurons and neuronal migration. Affects migration of sympathetic preganglionic neurons in the spinal cord, where it seems to act as a barrier to neuronal migration. Enzymatic activity is important for the modulation of cell adhesion. Binding to the extracellular domains of lipoprotein receptors VLDLR and LRP8/APOER2 induces tyrosine phosphorylation of DAB1 and modulation of TAU phosphorylation (By similarity).

Subcellular location: Extracellular, Secreted

Synonyms: RL, ETL7, LIS2, PRO1598, Reelin, RELN

Gene ID: 5649

UniProt: P78509

Pathways: Synaptic Membrane