SFTPD antibody (AA 301-375)

Catalog No. ABIN731678

The Rabbit Polyclonal anti-SFTPD antibody has been validated for WB, ELISA, IHC (p), IHC (fro), IF (p) and IF (cc). It is suitable to detect SFTPD in samples from Human, Rat and Mouse. There are 4+ publications available.

Quick Overview for SFTPD antibody (AA 301-375) (ABIN731678)

Target: SFTPD (Surfactant Protein D (SFTPD))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SFTPD antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Product Details anti-SFTPD Antibody

Binding Specificity: AA 301-375

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SP-D

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-SFTPD antibody (ABIN731678)

Chen, Liu, Lu, Zhu, Tang, Wang, Lu: "Functional roles of C/EBPα and SUMO‑modification in lung development." in: International journal of molecular medicine, Vol. 40, Issue 4, pp. 1037-1046, (2018) (PubMed).

Furukawa, Nagaike, Ozaki: "Databases for technical aspects of immunohistochemistry." in: Journal of toxicologic pathology, Vol. 30, Issue 1, pp. 79-107, (2017) (PubMed).

Ferretti, Fortwendel, Gebb, Barrington: "Autoantibody-Mediated Pulmonary Alveolar Proteinosis in Rasgrp1-Deficient Mice." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 197, Issue 2, pp. 470-9, (2016) (PubMed).

Sung, Liang, Lee, Yen, Hsiao, Wang, Jiang-Shieh, Tsai, Chen: "The protective effect of eupafolin against TNF-?-induced lung inflammation via the reduction of intercellular cell adhesion molecule-1 expression." in: Journal of ethnopharmacology, Vol. 170, pp. 136-47, (2015) (PubMed).

Target Details for SFTPD

Target: SFTPD (Surfactant Protein D (SFTPD))

Alternative Name: SP-D/PSPD

Background:

Synonyms: SP-D, PSP-D, SFTP4, COLEC7, Pulmonary surfactant-associated protein D, Collectin-7, Lung surfactant protein D, SFTPD, PSPD

Background: Contributes to the lung's defense against inhaled microorganisms, organic antigens and toxins. Interacts with compounds such as bacterial lipopolysaccharides, oligosaccharides and fatty acids and modulates leukocyte action in immune response. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties.

Gene ID: 6441

UniProt: P35247